Endometriosis pain will always be a part of my life.
Days like this should be a bigger part.
Searching for
relief from your endometriosis pain?
Myfembree is proven to relieve 3 types of endometriosis pain.
during periods
between periods
during sex*
Myfembree is not a surgery, procedure, injection, or painkiller. It is a once-daily prescription pill designed to manage moderate to severe endometriosis pain.
What are the benefits of Myfembree?
In clinical studies, Myfembree was proven effective in providing meaningful endometriosis pain relief.
The two 6-month clinical studies involved 1,251 premenopausal women with moderate to severe endometriosis pain.
After taking Myfembree:
- 7out of10women felt
less period pain**At week 24, compared with
3 out of 10 women on placebo. - 6out of10women felt less
pain between periods††At week 24, compared with
4 out of 10 women on placebo.
Studies also proved that Myfembree reduced 3 types of endometriosis pain:
- 74%less pain
during periods‡
‡At week 24, compared with a 26% reduction on placebo. - 50%less pain
between periods§
§At week 24, compared with a 36% reduction on placebo. - 43%less pain
during sex‖¶
‖At week 24, compared with a 29% reduction on placebo.¶Based on those women who were engaging in sex at the start of and during clinical trials.
Myfembree reduced the overall impact endo pain had on daily activities such as:
Sitting, standing, walking, or exercising
Sleeping
Participating in leisure activities
Coping with pain
In studies, women were asked how often their endo pain made them unable to engage in daily activities in the last 4 weeks (e.g., attend a social event, do jobs around the house, sitting, exercising, sleeping).
Improved endo pain within 2 period cycles
While the studies were not specifically designed to determine how quickly Myfembree worked, some women started seeing an improvement in period pain at 2 months.
What causes endometriosis pain?
When you have endometriosis, the pain you experience is caused by the tissue similar to what lines the uterus growing outside of the uterus, leading to lesions and inflammation.
A hormone called estrogen contributes to the growth of these lesions. As your body passes through its natural menstrual cycle, changing levels of estrogen cause lesions to grow. That’s why you might feel endometriosis symptoms, including pain during your period, between periods, and even during sex.
How does Myfembree work to treat endometriosis pain?
Myfembree is a once-daily medication specifically designed to decrease moderate to severe endo pain throughout your cycle. Myfembree contains three key ingredients, designed to support an optimal hormone range that may help reduce endo pain.
Relugolix:
Reduces hormones, such as
estrogen, which reduces endo pain.
Norethindrone acetate:
May protect the uterus from the effect of estrogen alone.
Estradiol (an estrogen):
May reduce bone loss from relugolix alone.
What are the possible side effects with Myfembree?
In clinical trials, the safety of Myfembree was also studied.
The most common side effects
The most common side effects of taking Myfembree for moderate to severe endometriosis pain were headache; hot flushes, sweating, or night sweats; mood changes, including worsening depression; abnormal vaginal bleeding (bleeding that lasts too long, that is too heavy, or is unexpected); nausea; toothache; back pain; decreased interest in sex; joint pain; tiredness; and dizziness.
Serious side effects
Serious side effects were reported in 2.9% of women on Myfembree and 2.2% of women on placebo. Serious side effects were uterine hemorrhage, suicidal ideation, gallstones, and gallbladder inflammation.
Discontinuations
In clinical trials, 4.5% of women treated with Myfembree stopped taking it because of side effects, compared with 2.9% of women in the placebo group. The most common side effect that led to discontinuation for women taking Myfembree was mood-related disorders (1.7%).
